Mechanistic modeling of the retinogeniculate circuit in cat

Hans E. Plesser, Physics Section/ITF, Agricultural University of Norway, 1432 Ås, Norway
Gaute T. Einevoll, Physics Section/ITF, Agricultural University of Norway, 1432 Ås, Norway
Paul Heggelund, Department of Physiology, University of Oslo, 0317 Oslo, Norway

Neurocomputing 44-46, 973-978 (2002)

Abstract

An early version of a biologically realistic spike-based model for the X-on pathway of the retinogeniculate circuit is presented. The model comprises feedforward retinal connections to the lateral geniculate nucleus as well as intrageniculate inhibitory actions from dendro-dendritic structures (triads) and axonal output of interneurons. Neurons are modeled as leaky integrate-and-fire-or-burst neurons. A network model comprising XX neurons was implemented using the SYNOD neural network simulator and tested with circular-spot stimuli, and our example simulations were able to reproduce corresponding experimental data.